MSEA

- Deprecated

Website

http://www.msea.ca/MSEA/faces/Home.jsp

Description

Metabolite Set Enrichment Analysis (MSEA) offers three kinds of enrichment analysis: overrepresentation analysis (ORA), single sample profiling (SSP) and quantitative enrichment analysis (QEA, based on the globaltest algorithm). When only a compound list is available ORA is performed, when compound names and concentrations are available SSP is performed and when concentrations are available for multiple samples QEA is performed. Pathways were generated using HMDB (location), MIC, Pubmed and SMPDB (pathway based). Bonferroni correction or FDR can be applied to p-values. R scripts used in the analysis are available to download. As of 2011 MSEA is part of MetaboAnalyst.

Functionality

• Pathway Analysis/Metabolite Set Enrichment Analysis

Instrument Data Type

Approaches

Computer Skills

Basic

Software Type

• Web App

Interface

• Web user interface

Operating System (OS)

• Unix/Linux
• Mac OS
• Windows

Language

R, Java

Dependencies

N/A

Input Formats - Open

List of compound IDs/ & concentrations

Input Formats - Proprietary

N/A

Published

2010

Last Updated

2012

License

Paper

http://www.ncbi.nlm.nih.gov/pubmed/20457745

PMID

20457745