ALEX

Version: 1

Website

http://mslipidomics.info/contents/?page_id=133

Description

Analysis of Lipid Experiments (ALEX) is designed for metabolite identification of multiplexed FT MS data. Lipids are identified using the ALEX lipid database containing >20,000 lipid species. This can be searched as part of the GUI or on a web-based tool, which requires a m/z list as input. For calibration of FT MS data, the identity of a well characterised lock-mass ion must be known for the online tool. For the pipeline it can be calculated automatically, using lock mass adjustment. A three-point quadratic interpolation is used for estimating the centroid m/z values of lock mass ions. Lipids can also be quantified using the Orange software.

Functionality

• Annotation

Instrument Data Type

• MS/DI-MS/Orbitrap DI-MS

Approaches

• Lipidomics/Targeted

Computer Skills

Advanced

Software Type

• Pipeline
• Python Package
• Web App

Interface

• Command line interface
• Web user interface

Operating System (OS)

Windows XP

Language

C++, Python, SQLite, PHP, Lisp

Dependencies

MSFileReader 2.2 (Thermo Scientific), Python 2.7, NumPy, PySide, comtypes, SciPy

Input Formats - Open

N/A

Input Formats - Proprietary

Thermo Fisher Scientific .raw

Published

2013

Last Updated

2013

License

Paper

http://www.ncbi.nlm.nih.gov/pubmed/24244551

PMID

24244551