Standardized Uptake Value (SUV) extension - QIICR/ProjectIssuesAndWiki GitHub Wiki

Objective

Design a 3D Slicer extension for calculation of PET Standardized Uptake Value (SUV)

Specific Tasks

  • Slicer CLI module for computing various types of SUV
  • Add capability to save the calculated scale factors as DICOM RWV IOD
  • Verify whether the types of SUVs that we need to encode are covered by the standard
  • Implement importer for RWV in Slicer

Contributors

  • Ethan Ulrich
  • Markus Van Tol
  • Reinhard R. Beichel
  • Andrey Fedorov

References

Validation

Executive Summary

The calculated SUV conversion factors were validated using a digital reference object (DRO). The SUVFactorCalculator module was applied to the DRO to calculate the four SUV conversion factors (body weight, body surface area, ideal body weight, lean body mass). Four SUV volumes were produced from the DICOM series using the formula SUVPixelValue = (OriginalPixelValue + RescaleIntercept) x RescaleSlope x SUVConversionFactor

Regions of interest for SUV comparison were 2D circles with radius 12.5, with the exception of region 6 being a sphere with radius 12.5.

The absolute difference between the calculated maximum SUV and the expected maximum SUV in each region of interest was less than 0.0001 for all SUV types (due to binary-decimal conversion). Rounded to 4 significant digits, the calculated maximum SUV is the same as the expected maximum SUV.

Documents