News and Features - PacificBiosciences/DevNet GitHub Wiki

Introducing the PacBio RS II and SMRT® Analysis v2.0.0.

April 11, 2013

Introducing the PacBio RS II, which still delivers the longest reads and 99.999% consensus accuracy, plus double the throughput of the original system. SMRT Analysis 2.0 is a pre-requisite for analyzing data from the PacBio RS II and include the following features:

  • Compatibility with increased throughput and larger data files from the PacBio RS II
  • Fully-integrated push-button microbial assembly with HGAP
  • Analyze fractionally modified base positions with chemistry-specific optimization
  • Streamlined reference sequence upload within SMRT Portal
  • Enhanced Quiver consensus in extended di-nucleotide repeats
  • Native browser support in stand-alone SMRT View

SMRT® Analysis Gets Smarter with v1.4.0 Update

January 31, 2013

SMRT Analysis gets smarter! Announcing SMRT Analysis v1.4.0, an update that achieves:

  • 99.999% accurate sequencing results
  • De novo assemblies from a single library prep
  • Full-length cDNA transcript analysis
  • Barcoding support
  • Improvements to base modification analysis for bacterial methylomes
  • Stand-alone SMRT View for Mac, Windows and Linux

Watch the webinar for an overview.

Download the software and read the documentation on PacBio DevNet.

XL Chemistry and Instrument Software v1.3.3

Nov. 5, 2012

XL chemistry and upgraded instrument software for extraordinarily long reads.

  • Faster chemistry to read more bases in a given duration of time
  • Stage start to capture early bases closer to the 5’ adaptor
  • Extended movie times of up to 120 minutes

XL is ideal for applications that benefit from extremely long reads, such as de novo assembly.

SMRT® Analysis v1.3.3

Oct 15, 2012

This update to SMRT Analysis brings new features:

  • Bacterial methylation: 5-mC, 6-mA, 4-mC
  • Methyltransferase motif analysis and visualization
  • pacBioToCA and Celera Assembler are bundled
  • Minor and compound variant detection analysis protocol
  • Scaled up AHA to scaffold genomes of up to 200 Mb