CalciumChannel - Overdrive77/BioSynapStudio-Public GitHub Wiki

CalciumChannel Class

Summary

Represents a calcium ion (Ca²⁺) channel in the neuron’s membrane. This voltage-gated channel opens during depolarization and contributes to spike dynamics and secondary messenger signaling.

Namespace

BioSynapStudio.Net.Modules.Channels

Assembly

BioSynapStudio.Net.dll

Inheritance

Identity → IonChannel → CalciumChannel

Behavior

Reversal Potential: +120 mV
Conductance Max: 1.0 (low)
Closed at: Resting, Reset states
Opens at: Graded, Action states
Gating Variable: Uses a simplified sigmoidal activation curve (c) updated every tick.

Properties

Name	Type	Description
`ReversalPotential`	`double`	Set to `+120 mV`, representing a strong inward driving force for Ca²⁺.
`ConductanceMax`	`double`	Set to `1.0`. Calcium channels typically have low conductance.
`Name`	`string`	Identified as `"Ca2+"`. Inherited from `Identity`.

Methods

Name	Signature	Description
`GetCurrent`	`override double GetCurrent(PotentialType potential, double V, double tick)`	Returns the calcium current using a simplified sigmoid gating mechanism. Returns `0.0` if at Resting or Reset phase.

Usage Example

var channel = new CalciumChannel();
double current = channel.GetCurrent(PotentialType.Graded, Vm: -40, tick: 125.0);

Remarks

The channel’s gating variable c gradually approaches c∞, modeled by a sigmoid curve dependent on voltage.
Returns negative current (inward Ca²⁺ flow) during depolarized states.
The channel’s opening probability increases rapidly with depolarization, mimicking biological calcium influx.

Legal Notice

This software constitutes original intellectual property of the author, protected under international copyright and patent law. Patent: GB2506327.2 – Synthesized Emotional Cognition (SEC) DOI: 10.17605/OSF.IO/XERKF