1.3 Difference between DNA and RNA - Oronda/Molecular_biology_concepts GitHub Wiki

The main differences include;

• DNA is double stranded while RNA is single stranded
• DNA has thymine nitrogenous base while RNA has uracil
• RNA has an -OH in the 3rd carbon sugar while DNA lacks an O molecule in its 3rd carbon sugar
• DNA is very stable at alkaline conditions but RNA is very unstable
• DNA is destroyed by DNAses while RNA is denatured by RNAses
• DNA is confined in the nucleus while RNA is found mainly in the cytoplasm
• DNA is responsible for storing and transferring genetic information, while RNA directly codes for amino acids and acts as a messenger between DNA and ribosomes to make proteins.