Adverse events and other Conditions - OHDSI/ETL--PulmonaryHypertensionRegistries GitHub Wiki

Information about adverse events is a valuable part of clinical trial or registry data. It is captured in a different way than conditions since each adverse event has many additional qualifiers indicating its severity, causality, relation to the study drug, outcome, etc. These qualifiers should not be omitted during the ETL. Some ideas on how to keep such data in the OMOP CDM are discussed in the How To Link Facts chapter.

Another important thing to note here is that adverse events can be mapped to domains other than Condition. This is not rare for cases when AEs are coded with MedDRA. For MedDRA mapping, see here.

Details on how to map Pulmonary Hypertension can be found in a separate chapter.

As for other conditions, their target domain depends on two factors: availability of a date of the event and target concept id of the event. If the date is not available, the only option is to store such an event as a 'History of' observation with the appropriate value as concept id (see Medical History). If the date is available, then populate an event table depending on the target domain.