Norovirus dengue and COX1 version history - NLM-DIR/vadr GitHub Wiki

Version history of the VADR versions, models and options GenBank has used to automatically process norovirus, dengue virus and COX1 submissions.

Version history for GenBank submission processing

Dates below are deployment dates (when the build became live for GenBank submission processing), which are not always the date the build was made. A row appears whenever the VADR version, the models version, or the command-line options changed for that virus. Where the options did not change from the row above, the cell reads no change.

Norovirus

date vadr version models version command-line options notes
Jun 22, 2020 1.1 1.1-1 --group Norovirus
Jul 28, 2020 1.1.1 1.1-1 no change
Dec 3, 2020 1.1.2 1.1-1 --group Norovirus --nomisc --noprotid
Feb 19, 2021 1.1.3 1.1-1 no change
Apr 13, 2021 1.2 calici-1.2-1 no change
Aug 5, 2021 1.3 calici-1.2-1 --split --cpu 1 --group Norovirus --nomisc --noprotid
Dec 23, 2021 1.4 calici-1.2-1 no change
Jan 11, 2022 1.4.1 calici-1.2-1 no change
Jul 11, 2022 1.4.2 calici-1.2-1 no change
May 15, 2024 1.6.3 calici-1.2-1 adds -r
March 12, 2026 1.7 calici-1.2-1 no change
Sep 3, 2026 1.7 calici-1.7-2 no change
Oct 8, 2026 1.7.3 calici-1.7-2 no change

Dengue

date vadr version models version command-line options notes
Jun 22, 2020 1.1 1.1-1 --group Dengue
Jul 28, 2020 1.1.1 1.1-1 no change
Dec 3, 2020 1.1.2 1.1-1 --group Dengue --nomisc --noprotid
Feb 19, 2021 1.1.3 1.1-1 no change
Apr 13, 2021 1.2 flavi-1.2-1 adds --mkey flavi
Aug 5, 2021 1.3 flavi-1.2-1 adds --split --cpu 1
Dec 23, 2021 1.4 flavi-1.2-1 no change
Jan 11, 2022 1.4.1 flavi-1.2-1 no change
Jul 11, 2022 1.4.2 flavi-1.2-1 no change
May 15, 2024 1.6.3 flavi-1.2-1 adds -r
March 12, 2026 1.7 flavi-1.2-1 no change
Oct 8, 2026 1.7.3 flavi-1.2-1 no change

COX1

date vadr version models version command-line options notes
Jun 22, 2020 1.1 cox1-1.1-1 --xmaxdel 3 --xmaxins 3 --xlongest --mkey cox1 --alt_pass lowcovrg --alt_fail fsthicnf,fstlocnf --fstlowthr 0.0 --nomisc
Jul 28, 2020 1.1.1 cox1-1.1-1 no change
Dec 3, 2020 1.1.2 cox1-1.1-4 adds --fstminnt 5 --noprotid --xsub $VADRMODELDIR/cox1-1.1-4.phy.xsub
Feb 19, 2021 1.1.3 cox1-1.1-4 no change
Apr 13, 2021 1.2 cox1-1.2-1 --xsub path now cox1.phy.xsub
Aug 5, 2021 1.3 cox1-1.2-1 adds --split --cpu 4; frameshift alerts become fstlocfi,fstlocf5,fstlocf3 with --fstminnti/5/3 5
Dec 23, 2021 1.4 cox1-1.2-1 frameshift alerts collapse to fstlocfi,fstlocft with --fstminnti/--fstminntt 5
Jan 11, 2022 1.4.1 cox1-1.2-1 no change
Jul 11, 2022 1.4.2 cox1-1.2-1 no change
May 15, 2024 1.6.3 cox1-1.2-2 drops --xlongest; adds -r --noflank
March 12, 2026 1.7 cox1-1.2-2 no change
Oct 8, 2026 1.7.3 cox1-1.2-2 no change