Short link to this page: https://HumanMicrobiome.info/Sleep

• Reviews
• General

Reviews:

Review, 2020: Circadian rhythms and the gut microbiota: from the metabolic syndrome to cancer https://www.nature.com/articles/s41574-020-00427-4

Review, 2020: Disruption of Circadian Rhythms and Gut Motility. An Overview of Underlying Mechanisms and Associated Pathologies https://journals.lww.com/jcge/Abstract/publishahead/Disruption_of_Circadian_Rhythms_and_Gut_Motility_.97633.aspx

Review, 2019: Potential Role for the Gut Microbiota in Modulating Host Circadian Rhythms and Metabolic Health https://www.mdpi.com/2076-2607/7/2/41

Review, 2019: Microbiome diurnal rhythmicity and its impact on host physiology and disease risk http://embor.embopress.org/content/early/2019/03/15/embr.201847129

Review, 2016: The Metronome of Symbiosis: Interactions Between Microbes and the Host Circadian Clock: https://doi.org/10.1093/icb/icw067

General:

Gut microbe movements regulate host circadian rhythms (2016): https://medicalxpress.com/news/2016-12-gut-microbe-movements-host-circadian.html - Microbiota diurnal rhythmicity programs host transcriptome oscillations http://dx.doi.org/10.1016/j.cell.2016.11.003

The intestinal microbiota programs diurnal rhythms in host metabolism through histone deacetylase 3 (2019): https://www.science.org/doi/10.1126/science.aaw3134

Butyrate, a metabolite of intestinal bacteria, enhances sleep (May 2019, mice and rats) https://www.nature.com/articles/s41598-019-43502-1

Body clock affects how the immune system works. (Jan 2020, mice) https://theconversation.com/body-clock-affects-how-the-immune-system-works-new-findings-129289 The clock gene Bmal1 inhibits macrophage motility, phagocytosis, and impairs defense against pneumonia.

Gut microbiota depletion by chronic antibiotic treatment alters the sleep/wake architecture and sleep EEG power spectra in mice (Nov 2020) https://www.nature.com/articles/s41598-020-76562-9

Chronic paradoxical sleep deprivation-induced depression-like behavior, energy metabolism and microbial changes in rats (April 2019) https://www.sciencedirect.com/science/article/abs/pii/S0024320519302565 "These data suggest that a specific situation of circadian disturbance, chronic PSD-induced alterations in gut microbiota and related host changes in metabolism may be the pathogenesis of depression"

Gut microbiome diversity associates with sleep quality in healthy adults https://www.gutmicrobiotaforhealth.com/en/gut-microbiome-diversity-associates-with-sleep-quality-in-healthy-adults/ Gut microbiome diversity is associated with sleep physiology in humans (Oct 2019)

Light-entrained and brain-tuned circadian circuits regulate ILC3s and gut homeostasis (2019, mice) https://www.nature.com/articles/s41586-019-1579-3

The circadian clock regulates the diurnal levels of microbial short-chain fatty acids and their rhythmic effects on colon contractility in mice (2018): https://onlinelibrary.wiley.com/doi/10.1111/apha.13193

Transplanted gut bacteria causes cardiovascular changes in mice (Aug 2022) https://www.eurekalert.org/news-releases/963863 Gut microbiota mediate vascular dysfunction in a murine model of sleep apnea: effect of probiotics

---

Search results for "sleep": https://old.reddit.com/r/HumanMicrobiome/search?q=sleep&restrict_sr=on&sort=relevance&t=all

Search results for "circadian": https://old.reddit.com/r/HumanMicrobiome/search?q=circadian&restrict_sr=on&sort=relevance&t=all