Align files - Gu-Lab-RBL-NCI/TIE-database GitHub Wiki

A primary aim of the TIE database is to aggregate all miRNA isoforms detected in human tumors. The “Align files” page is an entry point for browsing the sequence variability of any given miRNA across this big pan-cancer dataset. This page displays the sequence and abundance of all isomiRs for the querying miRNA in all cancer types. Templated nucleotides, which can be mapped back to the genome, are displayed in capital case whereas non-templated nucleotides are shown in lowercase with a unique color designated for each nucleotide composition. The dot notation is used as a position holder for the alignment to the pri-miRNA sequence. Users can filter the results to visualize only isomiRs with templated nucleotides or non-templated nucleotides. The absolute amount and relative percentage of each isomiR are reported for each patient sample and for each cancer type.

  1. Align files section section align files
  2. Align files - Cancer type table section align files
  3. Align files - Cancer type pie chart comparison section align files
  4. Align files - Samples within cancer type table section align files
  5. Align files - Sample type pie chart comparison within cancer type section align files