Sequencing Coverage necessary for de novo assembly - Green-Biome-Institute/AWS GitHub Wiki

One obvious issue when it comes to assembly of a genome is the depth of coverage of your sequencing data. In order to create some sort of desired range, I've compiled a series of sources from industry and academia and their claims of the necessary sequencing depth for de novo assembly.

10X genomics, 38x - 56x: https://support.10xgenomics.com/de-novo-assembly/sequencing/doc/specifications-sequencing-requirements-for-de-novo-assembly#:~:text=Sequencing%20Depth,polymorphic%20organisms%2C%20we%20recommend%2056x.