FTDI Drivers flowchart Mac OS - FPGAwars/apio GitHub Wiki

iceprog requires all the drivers unloaded to detect the board
FTDIUSBSerialDriver is automatically loaded when the FTDI board is connected for the first time
AppleUSBFTDI is automatically loaded after unload FTDIUSBSerialDriver and reconnect the board
After unload AppleUSBFTDI no more drivers are loaded although the board is reconnected
In order to enable other FTDI devices, the drivers configuration must be restored
No kext configuration remains after reboot

Therefore, to create a good user experience, the next process must be run on each bitstream upload: