Styling Charts - DON-PHAM/EPPlus GitHub Wiki
Charts
EPPlus 5 supports over 100 new chart styles introduced in Excel 2016. These styles can be easily set by the new StyleManager either using the ePresetChartStyle enum or the Excel ChartStyle number.
//Add a column chart
var chart = ws.Drawings.AddBarChart("column3dChart", eBarChartType.ColumnClustered3D);
var serie = chart.Series.Add(ws.Cells[2, 7, 26, 7], ws.Cells[2, 6, 26, 6]);
serie.Header = "Order Value";
chart.SetPosition(0, 0, 8, 0);
chart.SetSize(1000, 300);
chart.Title.Text = "Column Chart 3D";
//Set style 9 and Colorful Palette 3
chart.StyleManager.SetChartStyle(ePresetChartStyle.Bar3dChartStyle9, ePresetChartColors.ColorfulPalette3);
See Charts & Themes sample .NET Framework or Charts & Themes sample .NET Core