Bad Bugs - AguaClara/SWOT GitHub Wiki

Bad bugs (information reorganized from the FDA Bad Bug Book)

* waterborne rating created by Monroe based on quick scan of FDA description.

PATHOGENIC BACTERIA

Organism

Infective dose

waterborne*

Salmonella spp. (typhoid)

As few as 15-20 cells

yes

Clostridium botulinum

a very small amount (a few nanograms) of toxin can cause illness

no

Staphylococcus aureus

a toxin dose of less than 1.0 microgram in contaminated food will produce symptoms of staphylococcal intoxication. This toxin level is reached when S. aureus populations exceed 100,000 per gram

no

Campylobacter jejuni

about 400-500 bacteria

yes

Yersinia enterocolitica and Yersinia pseudotuberculosis

Unknown

possibly

Listeria monocytogenes

fewer than 1,000 total organisms may cause disease

possibly

Vibrio cholerae O1

one million organisms

yes

Vibrio cholerae non-O1

more than one million organisms

possibly

Vibrio parahaemolyticus and other vibrios

greater than one million organisms

no

Vibrio vulnificus

less than 100 total organisms

no

Clostridium perfringens

greater than 100 million organisms

no

Bacillus cereus

greater than one million organisms/g (of food)

no

Aeromonas hydrophila and other spp.

unsuccessful even at high doses

possibly

Plesiomonas shigelloides

greater than one million organisms

yes

Shigella spp.

10 cells

yes

Miscellaneous enterics

unknown

possibly

Streptococcus

no

ENTEROVIRULENT ESCHERICHIA COLI GROUP (EEC Group)

Organism

Infective dose

waterborne

Escherichia coli - enterotoxigenic (ETEC)

100 million to 10 billion bacteria

yes

Escherichia coli - enteropathogenic (EPEC)

EPEC are highly infectious for infants and the dose is presumably very low. In the few documented cases of adult diseases, the dose is presumably similar to other colonizers (greater than 10^6 total dose).

yes

Escherichia coli O157:H7 enterohemorrhagic (EHEC)

possibly as few as 10 organisms

possibly

Escherichia coli - enteroinvasive (EIEC)

possibly as few as 10 organisms

possibly

PARASITIC PROTOZOA and WORMS

Organism

Infective dose

waterborne

Giardia lamblia

one or more cysts

yes

Entamoeba histolytica

one viable cyst

yes

Cryptosporidium parvum

one organism

yes

Cyclospora cayetanensis

?

?

Anisakis sp. and related worms

 

no

Diphyllobothrium spp.

 

no

Nanophyetus spp.

 

no

Eustrongylides sp.

One live larva can cause an infection

no

Acanthamoeba and other free-living amoebae

 

(inhalation)

Ascaris lumbricoides and Trichuris trichiura

 

no

VIRUSES

Organism

Infective dose

waterborne

Hepatitis A virus

10-100 virus particles

yes

Hepatitis E virus

unknown

yes

Rotavirus

10-100 infectious viral particles

possibly

Norwalk virus group

presumed to be low

yes

Other viral agents

 

 

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