Setup - 987123879113/pcsx2 GitHub Wiki
What version to use?
If you need Linux or MacOS support, use the Qt build.
If you need to use the debugger, use the wxWidgets build.
If you're on Windows and don't need the debugger, you can use either the Qt or wxWidgets builds but the Qt build is recommended.
Qt
Instructions for the Qt build of PCSX2 P2IO fork can be found here.
wxWidgets
Instructions for the wxWidgets build of PCSX2 P2IO fork can be found here.