---
bibliography: 'morinlab.bib'
csl: 'NLM.csl'
link-citations: true
nocite: |
  @loveGeneticLandscapeMutations2012, 
---
[[_TOC_]]



## Relevance tier by entity

[[include:tables/table1_POR.md]]

## Warnings

<<Warn("The variants reported in this gene failed QC")>>

## Mutation incidence in large patient cohorts (GAMBL reanalysis)

|Entity|source               |frequency (%)|
|:------:|:---------------------:|:-------------:|
|BL    |GAMBL genomes+capture|2.54         |
|BL    |Thomas cohort        |  NA         |
|BL    |Panea cohort         |  NA         |

## Mutation pattern and selective pressure estimates

[[include:tables/dnds_POR.md]]



[[include:tables/browser_POR.md]]

## Expression
![](images/gene_expression/POR_by_pathology.svg)
<!-- ORIGIN: loveGeneticLandscapeMutations2012 -->
<!-- BL: loveGeneticLandscapeMutations2012 -->

## Representative Mutations

![](primary/Love_POR.svg)
**Rating**
&starf; &star; &star; &star; &star;


[[include:tables/mermaid_POR.md]]

## References