---
bibliography: 'morinlab.bib'
csl: 'NLM.csl'
link-citations: true
nocite: |
  @pasqualucciAnalysisCodingGenome2011, 
---
[[_TOC_]]

## Overview
The prevalence of MYOM2 mutations in DLBCL varies across studies. The role of these mutations in lymphomagenesis has not been thoroughly explored. 


## Relevance tier by entity

[[include:tables/table1_MYOM2.md]]

## Mutation incidence in large patient cohorts (GAMBL reanalysis)

|Entity|source        |frequency (%)|
|:------:|:--------------:|:-------------:|
|DLBCL |GAMBL genomes |3.25         |
|DLBCL |Schmitz cohort|8.09         |
|DLBCL |Reddy cohort  |3.20         |
|DLBCL |Chapuy cohort |4.27         |

## Mutation pattern and selective pressure estimates

[[include:tables/dnds_MYOM2.md]]




[[include:tables/browser_MYOM2.md]]

## Expression
![](images/gene_expression/MYOM2_by_pathology.svg)
<!-- ORIGIN: pasqualucciAnalysisCodingGenome2011 -->
<!-- DLBCL: pasqualucciAnalysisCodingGenome2011 -->

[[include:tables/mermaid_MYOM2.md]]

## References