---
bibliography: 'morinlab.bib'
csl: 'NLM.csl'
link-citations: true
nocite: |
  @chapuyMolecularSubtypesDiffuse2018, 
---
[[_TOC_]]



## Relevance tier by entity

[[include:tables/table1_DOCK1.md]]

## Mutation incidence in large patient cohorts (GAMBL reanalysis)

|Entity|source        |frequency (%)|
|:------:|:--------------:|:-------------:|
|DLBCL |GAMBL genomes | 3.82        |
|DLBCL |Schmitz cohort|10.21        |
|DLBCL |Reddy cohort  | 4.90        |
|DLBCL |Chapuy cohort | 5.98        |

## Mutation pattern and selective pressure estimates

[[include:tables/dnds_DOCK1.md]]




[[include:tables/browser_DOCK1.md]]

## Expression
![](images/gene_expression/DOCK1_by_pathology.svg)
<!-- ORIGIN: chapuyMolecularSubtypesDiffuse2018b -->
<!-- DLBCL: chapuyMolecularSubtypesDiffuse2018b -->

## All Mutations

[DLBCL-RICOVER_107-Tumor](https://bcgsc.ca/downloads/morinlab/GAMBL/Chapuy_2018/DLBCL-RICOVER_107-Tumor.html)
[DLBCL-RICOVER_253-Tumor](https://bcgsc.ca/downloads/morinlab/GAMBL/Chapuy_2018/DLBCL-RICOVER_253-Tumor.html)
[DLBCL-RICOVER_299-Tumor](https://bcgsc.ca/downloads/morinlab/GAMBL/Chapuy_2018/DLBCL-RICOVER_299-Tumor.html)
[DLBCL-RICOVER_338-Tumor](https://bcgsc.ca/downloads/morinlab/GAMBL/Chapuy_2018/DLBCL-RICOVER_338-Tumor.html)
[DLBCL-RICOVER_522-Tumor](https://bcgsc.ca/downloads/morinlab/GAMBL/Chapuy_2018/DLBCL-RICOVER_522-Tumor.html)
[DLBCL-RICOVER_773-Tumor](https://bcgsc.ca/downloads/morinlab/GAMBL/Chapuy_2018/DLBCL-RICOVER_773-Tumor.html)
[DLBCL-RICOVER_977-Tumor](https://bcgsc.ca/downloads/morinlab/GAMBL/Chapuy_2018/DLBCL-RICOVER_977-Tumor.html)

[[include:tables/mermaid_DOCK1.md]]

## References